Biotin-Beta-Amyloid 1-42 | Biotin-Aβ 1-42
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作者:jienitai
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发布时间: 2019-10-15
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1092 次浏览
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Biotin-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Biotin - Beta-Amyloid 1-42 | Biotin - Aβ 1-42
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| 货号 | 数量 | 价格（元） | 货期 |
| BA-42-T-1 | 1 mg | ￥900.00 | 1~2天 |
| BA-42-T-5 | 5 mg | 询价 | 1~2天 |
| BA-42-T-10 | 10 mg | 询价 | 1~2天 |
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| | 纯度： | >95% |
| | 序列： | Biotin-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
| | | Biotin-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala |
| | CAS No.: | / |
| | 分子式： | 102577-21-9 |
| | 分子量： | 4740.4 |
| | 等电点： | 4.7 |
| | 净电荷(PH=7)： | -3.7 |
| | 平均亲水性： | -0.1 |
| | 亲水残基比例： | 31% |
| | 外观： | 白色粉末 |
| | 盐： | TFA |
| | 来源： | 化学合成 |
| | 储存条件(冻干粉)： | -20°C（1年） 或 -80°C（1-2年） |
| | 溶解条件： | Acetic acid/water (3:2) or DMSO |
| | 运输条件： | 常温（加冰袋） |
| | 描述： | Biotin (N-terminus) labeled Beta-amyloid 1-42 (Aβ 1-42).
Beta amyloid 1−42 (Aβ1-42) is a self-associating peptide whose
neurotoxic derivatives are thought to play a role in Alzheimer’s
pathogenesis. |
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| | 参考： | 1, Diffusible, nonfibrillar ligands derived from Aβ1–42
are potent central nervous system neurotoxins
M. P. Lambert, A. K. Barlow, B. A. Chromy, C. Edwards and W. L. Klein;
PNAS May 26, 1998 95 (11) 6448-6453
2, Self-Assembly of Aβ1-42 into Globular Neurotoxins
Brett A. Chromy, Richard J. Nowak, Mary P. Lambert and William L. Klein;
Biochemistry 2003, 42, 44, 12749–12760
3, High-Level Neuronal Expression of Aβ1–42 in Wild-Type Human Amyloid
Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque
Formation
Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu, Margaret Mallory, Edward M.
Rockenstein, Kelly Johnson-Wood and Lisa McConlogue; Journal of
Neuroscience 1 June 2000, 20 (11) 4050-4058 |
