FITC-Beta-Amyloid 1-42 | Beta-Amyloid 1-42, FITC Labeled

		货号	数量	价格（元）	货期
		FA-42-T-1	1 mg	￥1500.00	1~2天
		FA-42-T-5	5 mg	询价	1~2天
		FA-42-T-10	10 mg	询价	1~2天
	纯度：	>95%
	序列：	FITC-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
		Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile- Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
	CAS No.:	/
	分子式：	C230H333N57O66S1
	分子量：	5016.68
	外观：	黄色粉末
	盐：	TFA
	储存条件(冻干粉)：	-20°C（1年） 或 -80°C（1-2年）
	溶解条件：	Acetic acid/water (3:2) or DMSO
	运输条件：	常温（加冰袋）
	描述：	Fluorescein labeled Beta-amyloid 1-42(Aβ1-42). Aβ1-42 is a major cause of Alzheimer,s Disease(AD) ,It is the main component of senile plaques,which is thought to exert toxic effects toward neurons. Expressed in all fetal tissues examined with highest levels in brain, kidney, heart and spleen. In adult brain, highest expression found in the frontal lobe of the cortex and in the anterior perisylvian cortex-opercular gyri.
	Product Citations：	Role of membrane GM1 on early neuronal membrane actions of Aβ during onset of Alzheimer's disease(2017) Product Name: FITC-Aβ42 and FAM-Aβ42(GenicBio) Author List: E.J.Fernández-Pérez, F.J.Sepúlveda, R.Peoples, L.G.Aguayo Journal: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Volume 1863, Issue 12, December  2017, Pages 3105-3116 Doi: https://doi.org/10.1016/j.bbadis.2017.08.013
		Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity Product Name: FITC-Aβ42 and Aβ42(GenicBio) Author List: Clemens Falker, Alexander Hartmann, Inga Guett, Frank Dohler, Hermann Altmeppen, Christian Betzel, Robin Schubert, Dana Thurm, Florian Wegwitz, Pooja Joshi, Claudia Verderio, Susanne Krasemann, Markus Glatzel. Journal: Journal of Neurochemistry. Volume137, Issue1. April 2016. Pages 88-100 Doi: https://doi.org/10.1111/jnc.13514 Citations: 104
		Abrogation of type-I interferon signalling alters the microglial response to Aβ1–42 Product Name: FITC-Aβ42 and Aβ42(GenicBio) Author List: Zachery Moore, Frank Mobilio, Frederick R. Walker, Juliet M. Taylor. Journal: Nature, Scientific Reports volume 10, Article number: 3153 (2020)
		TRPV1 regulates ApoE4-disrupted intracellular lipid homeostasis and decreases synaptic phagocytosis by microglia Product Name: FITC-Aβ42 and Aβ42(GenicBio) Author List: Chenfei Wang, Jia Lu, Xudong Sha, Yu Qiu, Hongzhuan Chen, Zhihua Yu. Journal: Experimental & Molecular Medicine volume 55, pages 347–363 (2023)
		Alzheimer's Aβ interacts with cellular prion protein inducing neuronal membrane damage and synaptotoxicity Product Name: FITC-Aβ42 and Aβ42(GenicBio) Author List: Christian Peters, María Paz Espinoza, Scarlet Gallegos, Carlos Opazo, Luis G. Aguayo. Journal: Neurobiology of Aging. Volume 36, Issue 3, March 2015, Pages 1369-1377. Doi: https://doi.org/10.1016/j.neurobiolaging.2014.11.019 Citations: 51
		Interrogation of human microglial phagocytosis by CRISPR genome editing Product Name: FITC-Aβ42 or Aβ42(GenicBio) Author List: Jason Cheng-Yu Chang, Cheng-You Wang, and Steven Lin. Journal: Front Immunol. 2023; 14: 1169725. Doi: 10.3389/fimmu.2023.1169725
		Phagocytosis of Apoptotic Cells Is Specifically Upregulated in ApoE4 Expressing Microglia in vitro Product Name: FITC-Aβ42 and Aβ42(GenicBio) Author List: Christiane Muth. Alexander Hartmann. Diego Sepulveda-Falla. Markus Glatzel.Susanne Krasemann Journal: Front. Cell. Neurosci., 03 May 2019. Sec. Cellular Neurophysiology. Volume 13 - 2019 Doi: https://doi.org/10.3389/fncel.2019.00181 Citations: 33
		Differential Membrane Toxicity of Amyloid-β Fragments by Pore Forming Mechanisms Product Name: FITC-Aβ42 and Aβ42(GenicBio) Author List: Peters, Christian | Bascuñán, Denisse | Opazo, Carlos1 | Aguayo, Luis G. Journal: Journal of Alzheimer's Disease, vol. 51, no. 3, pp. 689-699, 2016 Doi: 10.3233/JAD-150896 Citations: 56
		ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer’s disease models Product Name: FITC-Aβ42 and Aβ42(GenicBio) Author List: Yuanyuan Zhao. Di Hu. ....Drew J. Adams, Rong Xu. Journal: Nature Communications volume 13, Article number: 1121 (2022) Citations: 20
		Dual role of cofilin in APP trafficking and amyloid‐β clearance(2019) Product Name: FITC-Beta-amyloid 1-42(GenicBio) Author List: Tian Liu, Jung‐A. A. Woo, Yan Yan, Patrick LePochat, Mohammed Zaheen Bukhari, David E. Kang Journal: The FASEB Journal Doi: https://doi.org/10.1096/fj.201901268R

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