Beta-Amyloid 25-35 | Aβ 25-35
来源:
|
作者:jienitai
|
发布时间: 2020-10-03
|
1444 次浏览
|
分享到:
GSNKGAIIGLM
Beta-Amyloid 25-35 | Aβ 25-35
|
|
|
|
|
| 货号
| 数量
| 价格（元）
| 货期
|
|
|
| A-25-35-T-1
| 1 mg
| ￥200.00
| 1~2天
|
|
|
| A-25-35-T-5
| 5 mg
| 询价
| 1~2天
|
|
|
| A-25-35-T-10
| 10 mg
| 询价
| 1~2天
|
|
|
| 英文别名：
| Aβ 25-35 | Aβ 25-35 | Abeta
25-35 | Amyloid-β 25-35 | β-Amyloid
25-35
|
|
| 中文名：
| β-淀粉样多肽 25-35 | Beta-淀粉样多肽
25-35 | Beta-淀粉样多肽
25-35 | Β-淀粉样多肽 25-35 | Beta-Amyloid多肽 25-35
|
|
| 纯度：
| >95% by HPLC
|
|
| 序列(单字母)：
| GSNKGAIIGLM
|
|
| (三字母序列)：
| Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met
|
|
| CAS No.：
| 131602-53-4
|
|
| 分子式：
| C45H81N13O14S
|
|
| 分子量：
| 1060.28
|
|
| 外观：
| 白色粉末
|
|
| 等电点：
| 10.1
|
|
| 净电荷(PH=7)：
| 1.0
|
|
| 平均亲水性：
| -0.3
|
|
| 亲水残基比例：
| 27%
|
|
| 盐：
| TFA
|
|
| 来源：
| 化学合成
|
|
| 储存条件(冻干粉)：
| -20°C（1年） 或 -80°C（1-2年）
|
|
| 溶解条件：
| Acetic acid/water (3:2) or DMSO
|
|
| 运输条件：
| 常温（加冰袋）
|
|
| 描述：
| The fragment Aβ(25–35) of
the Alzheimer's amyloid β -peptide, like its full-length peptide
Aβ(1–42), has shown neurotoxic activities in cultured cells. But it
differs from all the other commonly studied β-amyloid peptides because
of its extremely rapid aggregation properties and enhanced
neurotoxicity.Aβ(25–35) is able to cause memory impairment and
neurodegenerative events.
|
|
| 分子结构：
| 
|
|
| 参考：
| 1, Rapid aggregation and
assembly in aqueous solution of Aβ (25–35) peptide.
Lia Millucci, Roberto Raggiaschi, Davide Franceschini, Georg Terstappen
& Annalisa Santucci; Journal of Biosciences volume 34,
pages293–303(2009)
2, Aβ(25–35) peptide displays H2O2-like reactivity towards aqueous FE2+,
nitroxide spin probes, Ant) synaptosomal membrane proteins.
D.Allan Butterfield; LauraMartin John M.Carney; Kenneth Hensley. Life
Sciences, Volume 58, Issue 3, 8 December 1995, Pages 217-228
3, Aβ (25–35) and its C‐and/or N‐blocked derivatives: Copper driven
structural features and neurotoxicity
Maria Laura Giuffrida Giulia Grasso Menotti Ruvo Carlo Pedone Angela
Saporito Daniela Marasco Bruno Pignataro Claudia Cascio Agata Copani
Enrico Rizzarelli. Neuroscience Research; Volume 85, Issue 3 15 February
2007. Pages 623-633
|
....................
