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上海捷妮泰生物科技有限公司
GenicBio
Beta-Amyloid 1-42 | Aβ 1-42(Human), HCl
来源:
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作者:jienitai
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发布时间: 2019-10-15
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1325 次浏览
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分享到:
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA ● HCl
Beta-Amyloid 1-42 | Aβ 1-42(Human), HCl
 | |||||
| 货号 | 数量 | 价格（元） | 货期 | ||
| A-42-H-1 | 1 mg | ￥1000.00 | 1~2天 | ||
| A-42-H-5 | 5 mg | 询价 | 1~2天 | ||
| A-42-H-10 | 10 mg | 询价 | 1~2天 | ||
| 英文别名： | Aβ 42 | Aβ1-42 | Abeta 42 | Abeta 1-42 | Amyloid-β 42 | β-Amyloid 1-42 | ||||
| 中文名： | β-淀粉样多肽 1-42 | Beta-淀粉样多肽 1-42 | Beta-淀粉样多肽 -42 | Β-淀粉样多肽(1-42) | Beta-Amyloid多肽(1-42) | ||||
| 纯度： | >95% by HPLC | ||||
| 序列(单字母)： | DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA ● HCl | ||||
| (三字母序列)： | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile- Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala | ||||
| CAS No.： | 107761-42-2 | ||||
| 分子式： | C203H311N55O60S | ||||
| 分子量： | 4514.14 | ||||
| 外观： | 白色粉末 | ||||
| 等电点： | 5.2 | ||||
| 净电荷(PH=7)： | -2.7 | ||||
| 平均亲水性： | -0.1 | ||||
| 亲水残基比例： | 31% | ||||
| 盐： | HCl | ||||
| 来源： | 化学合成 | ||||
| 储存条件(冻干粉)： | -20°C（1年） 或 -80°C（1-2年） | ||||
| 溶解条件： | Acetic acid/water (3:2) or DMSO | ||||
| 运输条件： | 常温（加冰袋） | ||||
| 描述： | 这条肽我们提供的是盐酸盐，TFA的含量小于1% | ||||
| 分子结构： | 
| ||||
| Product Citations | |||||
| 1,
Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in
Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired
ER Translocation (2020) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Behnam Mohammadi, Luise Linsenmeier,Mohsin Shafiq, etc. Journal: Journal of Molecular Neurobiology Doi: https://doi.org/10.1007/s12035-020-01917-2 | ||||
| 2, An
analog derived from phenylpropanoids ameliorates Alzheimer's
disease–like pathology and protects mitochondrial function (2019) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Shichao Huang,Xin Caob, Yue Zhou, Fuchun Shi, Gang Pei, etc. Journal: Neurobiology of Aging Doi: https://doi.org/10.1016/j.neurobiolaging.2019.05.002 | |||||
| 3,
Modulation of OSCP mitigates mitochondrial and synaptic deficits in a
mouse model of Alzheimer’s pathology(2019) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Esha Gauba, Shaomei Sui, Jing Tian, Christopher Driskill, etc. | |||||
| 4, The
Neuroprotective Action of Amidated-Kyotorphin on Amyloid β
Peptide-Induced Alzheimer’s Disease Pathophysiology(2020) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Rita F. Belo, Margarida L. F. Martins, Liana Shvachiy, etc. Journal: Front Pharmacol. 2020; 11: 985. Doi: 10.3389/fphar.2020.00985 | |||||
| 5, A pyrene-inhibitor
fluorescent probe with large Stokes shift for the staining of Aβ1–42, α-synuclein,
and amylin amyloid fibrils as well as amyloid- containing Staphylococcus aureus biofilms(2019) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Alejandro Mahía, María Conde-Giménez, Sandra Salillas, etc. Journal: Analytical and Bioanalytical Chemistry Doi: https://doi.org/10.1007/s00216-018-1433-8 | |||||
| 6, The
Effects of Cardiotrophin-1 on Early Synaptic Mitochondrial Dysfunction
and Synaptic Pathology in APPswe/PS1dE9 Mice(2017) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Wang, Dongmei; Liu, Xiaozhuan; Liu, Yumei; Li, Sanqiang; Wang, Chenying Journal: Journal of Alzheimer's Disease, vol. 59, no. 4, pp. 1255-1267, 2017 DOI: 10.3233/JAD-170100 | |||||
| 7, Effect
of Cholesterol on Membrane Fluidity and Association of Aβ Oligomers and
Subsequent Neuronal Damage: A Double-Edged Sword(2018) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Eduardo J. Fernández-Pérez, Fernando J. Sepúlveda, etc. Journal: Front. Aging Neurosci., 03 August 2018 Doi: https://doi.org/10.3389/fnagi.2018.00226 | |||||
| 8, A
Fluorescence‐Based Sensor Assay that Monitors General Protein
Aggregation in Human Cells(2018) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Marisa Pereira, Diogo Tomé, Ana S. Domingues, Ana S. Varanda, etc. Journal: Journal of Biotechnology Doi: https://doi.org/10.1002/biot.201700676 | |||||
| 9, Amyloid
aggregation and membrane activity of the antimicrobial peptide uperin
3.5(2018) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Lisandra L. Martin, Clemens Kubeil, Stefania Piantavigna, Tarun Tikkoo, etc. Journal: Journal of peptide science Doi: https://doi.org/10.1002/pep2.24052 | |||||
| 10,
Rapamycin protects against Aβ-induced synaptotoxicity by increasing
presynaptic activity in hippocampal neurons(2014) Product Name: Beta-amyloid 1-42(GenicBio) Author List: A.E.Ramírez， C.R.Pacheco，L.G.Aguayo Journal: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Doi: https://doi.org/10.1016/j.bbadis.2014.04.019 | |||||
| 11, Coat
protein I depletion-associated Golgi fragmentation in an Alzheimer's
disease model Product Name: Beta-amyloid 1-42(GenicBio) Author List: Mi Jeong Kim, A Reum Je, Hyo-Jeong Kim, etc. Journal: Journal of Animal Cells and Systems Doi: https://doi.org/10.1080/19768354.2014.984756 | |||||
| 12,
Alzheimer's Aβ interacts with cellular prion protein inducing neuronal
membrane damage and synaptotoxicity Product Name: Beta-amyloid 1-42(GenicBio) Author List: Christian Peters, María Paz Espinoza, Scarlet Gallegos, etc. Journal: Neurobiology of Aging Doi: https://doi.org/10.1016/j.neurobiolaging.2014.11.019 | |||||
| 13,
Levetiracetam inhibits oligomeric Aβ-induced glutamate release from
human astrocytes(2016) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Sara Sanz-Blasco, Juan C. Pi?a-Crespo, Xiaofei Zhang, Scott R. McKercher, etc. Journal: Journal of Neuroreport Doi: 10.1097/WNR.0000000000000601 | |||||
| 14,
Multifunctional Curcumin-Nanocarriers Based on Host-Guest Interactions
for Alzheimer Disease Diagnostic(2015) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Lamesh Ramdani, Romain Bourboulou, Mounir Belkouch, etc. Journal: Journal of Nanomedicine & Nanotechnology Doi: 10.4172/2157-7439.1000270 | |||||
| 15, The
membrane-active amphibian peptide caerin 1.8 inhibits fibril formation
of amyloid β1-42(2015) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Yanqin Liu, Tianfang Wang, Antonio N.Calabrese, John A.Carver, etc. Journal: Journal of Peptides; Volume 73, November 2015, Pages 1-6 Doi: https://doi.org/10.1016/j.peptides.2015.08.004 | |||||
| 16, Effects
of dipole modifiers on channel-forming activity of amyloid and amyloid-like
peptides in lipid bilayers(2015) Product Name: Beta-amyloid 1-42(GenicBio) Author List: S. S. Efimova, V. V. Zakharov & O. S. Ostroumova. Journal: Cell and Tissue Biology volume 9, pages250–259(2015) Doi: https://doi.org/10.1134/S1990519X15030049 | |||||
| 17,
Amyloid-beta oligomerization is associated with the generation of a
typical peptide fragment fingerprint(2016) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Nikita Rudinskiy | Christophe Fuerer | Davide Demurtas | Sebastian Zamorano, etc. Journal: Alzheimer's & Dementia; Volume 12, Issue 9, September 2016, Pages 996-1013 Doi: https://doi.org/10.1016/j.jalz.2016.03.011 | |||||
| 18,
Differential Membrane Toxicity of Amyloid-β Fragments by Pore Forming
Mechanisms(2016) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Peters, Christian | Bascu?án, Denisse | Opazo, Carlos | Aguayo, Luis G. Journal: Journal of Alzheimer's Disease, vol. 51, no. 3, pp. 689-699, 2016 | |||||
| 19,
Crystallization and preliminary X-ray diffraction analysis of the Fab
portion of the Alzheimer's disease immunotherapy candidate bapineuzumab
complexed with amyloid-[beta](2014) Product Name: Beta-amyloid 1-42(GenicBio) Author List: G. A. N. Crespi, D. B. Ascher, M. W. Parker and L. A. Miles Journal: CRYSTALLIZATION COMMUNICATIONS | |||||
| 20, Exosomal
cellular prion protein drives fibrillization of amyloid beta and
counteracts amyloid beta‐mediated neurotoxicity(2015) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Clemens Falker Alexander Hartmann Inga Guett Frank Dohler Hermann Altmeppen, etc. Journal: Journal of Neurochemistry Doi: https://doi.org/10.1111/jnc.13514 | |||||
| 21, Einfluss
der sauren Sphingomyelinase auf die Makrophagenaktivierung durch
Alzheimer Amyloid Protein (2012) Product Name: Beta-amyloid 1-42(GenicBio) Author List: Herrn Prof. Dr. Fa?bender, Herrn Dr. Liu und Herrn Dipl.-Biol. Xie danke ich vielmals Journal: der Medizinischen Fakult?t der UNIVERSIT?T DES SAARLANDES | |||||
