TAT(48-60), a cell penetrating peptide fragment of the Tat regulatory protein of the HIV virus, TAT(48-60) peptide (GRKKRRQRRRPPQ sequence) are most commonly utilized as cell penetrating peptides.

The cell-penetrating peptide Tat (48–60) (GRKKRRQRRRPPQ) derived from HIV-1 Tat protein showed potent antibacterial activity

源自HIV-1 Tat蛋白的细胞穿透肽Tat（48-60）（GRKKRRQRRRPPQ）显示出强大的抗菌活性

Cell penetrating peptides (CPP) are short cationic peptides that offer therapeutic use as drug cargoes through their innate ability to permeate the cell membrane. The tridecapeptide (GRKKRRQRRRPPQ) is a known sequence from the 86 to 102 amino acid long protein from the human immunodeficiency virus (HIV)-1 TAT at residues 48 to 60. This peptide has been shown to be an effective antibacterial agent and cellular translocation in the monomer form. Since better bactericidal action and permeation is observed in prior studies of the TAT to tetramer may further enhance the properties of the peptide. 

细胞穿透肽（CPP）是一种短阳离子肽，通过其固有的渗透细胞膜的能力作为药物载体提供治疗用途。十三肽（GRKKRRQRRRPPQ）是来自人类免疫缺陷病毒（HIV）-1 TAT的86至102个氨基酸长蛋白的已知序列，残基为48至60。该肽已被证明是一种有效的抗菌剂（在2-8μm处的MIC…），并以单体形式进行细胞移位。