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Beta-Amyloid 1-42 | Aβ 1-42, mouse, rat
来源:
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作者:jienitai
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发布时间: 2020-10-03
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816 次浏览
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DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Beta-Amyloid 1-42 | Aβ 1-42, mouse, rat
| 货号 | 数量 | 价格（元） | 货期 | ||
| A-42-M-1 | 1 mg | ￥1500.00 | 1~2天 | ||
| A-42-M-5 | 5 mg | 询价 | 1~2天 | ||
| A-42-M-10 | 10 mg | 询价 | 1~2天 | ||
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| 英文别名： | Aβ42 | Aβ1-42 | Abeta42 | Abeta 1-42 | Amyloid-β42 | β-Amyloid 1-42, mouse, rat | ||||
| 中文名： | 鼠：β-淀粉样多肽 1-42 | Beta-淀粉样多肽 1-42 | Beta-淀粉样多肽 -42 | Β-淀粉样多肽(1-42) | Beta-Amyloid多肽(1-42) | ||||
| 纯度： | >95% by HPLC | ||||
| 序列(单字母)： | DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA | ||||
| (三字母序列)： | H - Asp - Ala - Glu - Phe - Gly - His - Asp - Ser - Gly - Phe - Glu - Val - Arg - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH | ||||
| CAS No.： | / | ||||
| 分子量： | 4418.01 | ||||
| 外观： | 白色粉末 | ||||
| 等电点： | 4.7 | ||||
| 净电荷(PH=7)： | -2.8 | ||||
| 平均亲水性： | -0.1 | ||||
| 亲水残基比例： | 31% | ||||
| 盐： | TFA | ||||
| 来源： | 化学合成 | ||||
| 储存条件(冻干粉)： | -20°C（1年） 或 -80°C（1-2年） | ||||
| 溶解条件： | Acetic acid/water (3:2) or DMSO | ||||
| 运输条件： | 常温（加冰袋） | ||||
| 描述： | Insoluble deposits of β-amyloid (Aβ) are associated to neurodegenerative pathologies, in particular Alzheimer’s Disease (AD). The toxicity of synthetic amyloid-like peptides has been largely demonstrated and shown to depend upon their aggregation state. | ||||
| 参考： |
1, Anxiolytic and antidepressant profile of the
methanolic extract of Piper nigrum fruits in beta-amyloid (1–42) rat
model of Alzheimer’s disease Lucian Hritcu, Jaurès A Noumedem, Oana Cioanca, Monica Hancianu, Paula Postu & Marius Mihasan; Behavioral and Brain Functions; volume 11, Article number: 13 (2015) 2, Methanolic Extract of Piper nigrum Fruits Improves Memory Impairment by Decreasing Brain Oxidative Stress in Amyloid Beta(1–42) Rat Model of Alzheimer’s Disease Lucian Hritcu, Jaurès A. Noumedem, Oana Cioanca, Monica Hancianu, Victor Kuete & Marius Mihasan; Cellular and Molecular Neurobiology; volume 34, pages437–449(2014) 3，Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats S.Arancibia, M.Silhol, F.Moulière, J.Meffre, I.Höllinger, T.Maurice, L.Tapia-Arancibia; Neurobiology of Disease; Volume 31, Issue 3, September 2008, Pages 316-326 |
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